publication detail

Characterizing single sinonasal squamous cell carcinoma using dielectrophoresis and electrorotation

AUTHORS

  • Mai Thao N P
  • Bensalem Sakina
  • Thiebot Bénédicte
  • Manivet Philippe
  • Pelta Juan
  • Le Pioufle Bruno

KEYWORDS

  • Sinonasal squamous cell carcinomas
  • Di-electrophoresis
  • Electrorotation
  • Single cell analysis

    • Document type

    Conference papers

    Résumé

    We show the capture and analysis single cells, in particular human sinonasal squamous cell carcinomas (SCC), by the combination of di-electrophoresis (DEP) force and electrorotation, within a microfluidic device. A set of 4 planar polynomial electrodes was employed to perform nDEP trapping of two lines tumor cell with different invasivity, named NC5 and NC7. Once captured at the center of the electrodes set, electrorotation was served to extract the rotational speed's spectra. From the spectra, their electrophysiological properties can be estimated.

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